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Alternative medicine
By Mayo Clinic staff
Vitamin E
Some studies have shown that vitamin E can slow the progression of Alzheimer's disease, while other studies have shown no benefit. Doctors now warn people against taking large dosages of vitamin E, because it can increase your risk of cardiovascular death.
Ginkgo
Some people believe that extracts from the leaves of the ginkgo biloba tree may help slow the progression of memory problems associated with Alzheimer's disease. But a recent large-scale study showed no benefit. Be aware that these preparations can interact with blood-thinning medications and cause bleeding.
Huperzine A
Made from Chinese club moss, Huperzine A appears to work in ways similar to prescription cholinesterase inhibitors. Because of the increased risk of toxic side effects, you shouldn't take Huperzine A if you're also taking a drug like donepezil (Aricept).
- Alzheimer's disease fact sheet. National Institute on Aging. http://www.nia.nih.gov/Alzheimers/Publications/adfact.htm. Accessed Oct. 31, 2008.
- Shadlen MF, et al. Evaluation of cognitive impairment and dementia. http://www.uptodate.com/home/index.html. Accessed Nov. 3, 2008.
- Caselli RJ, et al. The degenerative dementias: Alzheimer's disease. In: Goetz CG, et al. Textbook of Clinical Neurology. 3rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/109112945-3/0/1488/287.html. Accessed Nov. 3, 2008.
- Alzheimer's information: Causes. National Institute on Aging. http://www.nia.nih.gov/Alzheimers/AlzheimersInformation/Causes/. Accessed Nov. 6, 2008.
- Shadlen MF, et al. Dementia syndromes. http://www.uptodate.com/home/index.html. Accessed Nov. 6, 2008.
- Basics of Alzheimer's disease: What it is and what you can do. Alzheimer's Association. http://www.alz.org/national/documents/brochure_basicsofalz_low.pdf. Accessed Nov. 6, 2008.
- Alzheimer's disease genetics fact sheet. National Institute on Aging. http://www.nia.nih.gov/Alzheimers/Publications/geneticsfs.htm. Accessed Nov. 6, 2008.
- Shadlen MF, et al. Risk factors for dementia. http://www.uptodate.com/home/index.html. Accessed Nov. 6, 2008.
- Kelley BJ, et al. Alzheimer's disease and mild cognitive impairment. Neurological Clinics. 2007;25:577.
- Late-stage care. Alzheimer's Association. http://www.alz.org/national/documents/brochure_latestage.pdf. Accessed Nov. 7, 2008.
- Dementia care practice recommendations for assisted living residences and nursing homes. Alzheimer's Association. http://www.alz.org/national/documents/brochure_DCPRphases1n2.pdf. Accessed Nov. 7, 2008.
- Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Nov. 7, 2008.
- Press D, et al. Cholinesterase inhibitors in the treatment of dementia. http://www.uptodate.com/home/index.html. Accessed Nov. 7, 2008.
- Press D, et al. Treatment of dementia. http://www.uptodate.com/home/index.html. Accessed Nov. 7, 2008.
- Press D, et al. Prevention of dementia. http://www.uptodate.com/home/index.html. Accessed Nov. 7, 2008.
- Natural medicines in the clinical management of Alzheimer's disease. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Nov. 10, 2008.
- Alexander M, et al. Patient information: Alzheimer's disease. http://www.uptodate.com/patients/content/topic.do?topicKey=~eWpcYl7lC9LRwe. Accessed Nov. 10, 2008.
- Press D, et al. Future directions in dementia treatments. http://www.uptodate.com/home/index.html. Accessed Nov. 7, 2008.
- Smith GE (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 19, 2008.
- DeKosky ST, et al. Ginkgo biloba for prevention of dementia: A randomized controlled trial. Journal of the American Medical Association. 2008;19:2253.
