Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedDefinition
By Mayo Clinic staffAnhidrosis is the inability to sweat normally. While this may not sound like a serious condition, anhidrosis can be life-threatening. When you don't perspire, your body can't cool itself, which can lead to overheating and sometimes to heatstroke — a potentially fatal condition.
Anhidrosis — sometimes called hypohidrosis — can be difficult to diagnose. Mild anhidrosis often goes unrecognized, and dozens of factors can cause the condition, including skin trauma and certain diseases and medications.
Treatment of anhidrosis involves addressing the underlying cause, if one can be found.
- Fealey RD, et al. Disorders of the eccrine sweat glands and sweating. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: McGraw-Hill Companies; 2008. http://www.accessmedicine.com/content.aspx?aID=2985825. Accessed Oct 8, 2009.
- No sweat? It's not always a dream come true. International Hyperhydrosis Society. http://www.sweatsolutions.org/SweatSolutions/Article.asp?ArticleCode=26497017&EditionCode=87373635. Accessed Oct. 9, 2009.
- More III JG. Disorders of the sweat glands. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/164330502-2/899438951/1608/1544.html. Accessed Oct. 8, 2009.
- Extreme heat: A prevention guide to promote your personal health and safety. Centers for Disease Control and Prevention. http://www.bt.cdc.gov/disasters/extremeheat/heat_guide.asp. Accessed Sept. 15, 2009.
- Saper CB. Autonomic disorders and their management. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier:2007. http://www.mdconsult.com/das/book/body/164330686-2/0/1492/1482.html?tocnode=5463. Accessed Oct. 8, 2009.
- Drugs/medications known to cause anhidrosis. International Hyperhydrosis Society. http://www.sweatsolutions.org/pdf/Anhidrosis.pdf. Accessed Oct. 9, 2009.
- Advice for older adults on staying safe in hot weather. National Institute on Aging. http://www.nia.nih.gov/NewsAndEvents/PressReleases/PR20080731hyperthermia.htm. Accessed Oct. 9, 2009.
- Zimmerman JL, et al. Hyperthermia. In: Hall JB, et al. Principles of Critical Care. 3rd ed. New York, N.Y.: McGraw-Hill Professional; 2005. http://www.accessmedicine.com/content.aspx?aID=2282701. Accessed July 7, 2009.