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Causes

By Mayo Clinic staff

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Illustration showing inflamed appendix
Appendicitis

The cause of appendicitis isn't always clear. Sometimes appendicitis can occur as a result of:

  • An obstruction. Food waste or a hard piece of stool (fecal stone) can become trapped in an orifice of the cavity that runs the length of your appendix.
  • An infection. Appendicitis may also follow an infection, such as a gastrointestinal viral infection, or it may result from other types of inflammation.

In both cases, bacteria may subsequently invade rapidly, causing the appendix to become inflamed and filled with pus. If not treated promptly, the appendix can rupture.

References
  1. Sarosi GA, et al. Appendicitis. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/147305686-2/0/1389/0.html. Accessed July 1, 2009.
  2. Ferri FF. Appendicitis, acute. In: Ferri FF. Ferri's Clinical Advisor 2009: Instant Diagnosis and Treatment. Philadelphia, Pa.: Mosby Elsevier; 2009. http://www.mdconsult.com/das/book/body/147002427-2/0/1701/0.html. Accessed July 1, 2009.
  3. Appendicitis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/appendicitis/. Accessed July 1, 2009.
  4. Appendectomy. American College of Surgeons. http://www.facs.org/public_info/operation/brochures/app.pdf. Accessed July 1, 2009.

DS00274

Aug. 15, 2009

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