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Complications
By Mayo Clinic staff
Increased risk of breast cancer
If you've been diagnosed with atypical hyperplasia, you have an increased risk of breast cancer in the future. Women with atypical hyperplasia have a risk of breast cancer that is four to fives times higher than that of women with no atypical hyperplasia.
Being diagnosed with atypical hyperplasia at a younger age may increase the risk of breast cancer even more. Women diagnosed with atypical hyperplasia before age 45 have the greatest risk of breast cancer, compared with older women, especially those older than 55.
- Non-cancerous breast conditions. American Cancer Society. http://www.cancer.org/docroot/CRI/content/CRI_2_6X_Non_Cancerous_Breast_Conditions_59.asp. Accessed Aug. 19, 2009.
- Miltenburg DM, et al. Benign breast disease. Obstetrics and Gynecology Clinics of North America. 2008;35:285.
- Hartmann LC, et al. Benign breast disease and the risk of breast cancer. The New England Journal of Medicine. 2005;353:229.
- London SJ, et al. A prospective study of benign breast disease and the risk of breast cancer. Journal of the American Medical Association. 1992;267:941.
- Degnim AC, et al. Stratification of breast cancer risk in women with atypia: A Mayo cohort study. Journal of Clinical Oncology. 2007;25:2671.
- Dupont WD, et al. Breast cancer risk associated with proliferative breast disease and atypical hyperplasia. Cancer. 1993;71:1258.
- Kiluk JV, et al. High-risk benign breast lesions: Current strategies in management. Cancer Control. 2007;14:321.
- Breast cancer screening and diagnosis. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/breast-screening.pdf. Accessed Aug. 21, 2009.
- Breast cancer risk reduction. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/breast_risk.pdf. Accessed Aug. 21, 2009.
