Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedSymptoms
By Mayo Clinic staffSigns and symptoms of autonomic neuropathy vary widely, depending on which parts of your autonomic nervous system are affected. They may include:
- Dizziness and fainting upon standing (orthostatic hypotension), caused by a drop in blood pressure
- Urinary problems, including difficulty starting urination, overflow incontinence and inability to empty your bladder completely, which can lead to urinary tract infections
- Sexual difficulties, including erectile dysfunction or ejaculation problems in men, and vaginal dryness and difficulties with arousal and orgasm in women
- Difficulty digesting food (gastroparesis), which can cause a feeling of fullness after eating little, loss of appetite, diarrhea, constipation, abdominal bloating, nausea, vomiting and heartburn
- Sweating abnormalities, especially decreased sweating, so the body can't regulate its temperature; also excessive sweating, sometimes after eating
- Sluggish pupil reaction, making it difficult to adjust from light to dark and causing difficulties with driving at night
- Exercise intolerance, when your heart rate remains unchanged instead of increasing and decreasing in response to your activity level
- Lack of usual warning signs of low blood sugar (hypoglycemia), which include shakiness, increased heart rate, sweating and palpitations