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  • With Mayo Clinic endocrinologist

    Maria Collazo-Clavell, M.D.

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Question

Caffeine: Does it affect blood sugar?

Does caffeine affect blood sugar?

Answer

from Maria Collazo-Clavell, M.D.

Caffeine impairs insulin action but not necessarily blood sugar (glucose) levels in young, healthy adults. However, if you have type 2 diabetes, the impact of caffeine on insulin action may be associated with a small but detectable rise in blood sugar levels, particularly after meals. About 250 milligrams of caffeine — or the equivalent of 2 to 2 1/2 cups (473 to 591 milliliters) of plain, brewed coffee — a day may cause this effect.

If you have type 2 diabetes and you're struggling to control your blood sugar levels, limiting the amount of caffeine in your diet may provide a benefit.

Next question
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References
  1. MacKenzie T, et al. Metabolic and hormonal effects of caffeine: Randomized, double-blind, placebo-controlled crossover trial. Metabolism. 2007;56:1694.
  2. Lane JD, et al. Exaggeration of postprandial hyperglycemia in patients with type 2 diabetes by administration of caffeine in coffee. Endocrine Practice. 2007;13:239.
  3. Tunnicliffe JM, et al. Coffee, glucose homeostasis, and insulin resistance: Physiological mechanisms and mediators. Applied Physiology, Nutrition and Metabolism. 2008;33:1290.
  4. USDA National Nutrient Database for Standard Reference, Release 22. U.S. Department of Agriculture. http://www.nal.usda.gov/fnic/foodcomp/search/. Accessed Jan. 27, 2010.

AN01804

Feb. 3, 2010

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