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Why it's done
By Mayo Clinic staffBlood and bone marrow donation provides blood stem cells for transplantation. In the past, all donors had to undergo surgery to draw bone marrow containing blood stem cells from the hipbones.
Today, however, it's more common to collect blood stem cells directly from the blood. This is called peripheral blood stem cell (PBSC) donation. Blood stem cells can also be collected from umbilical cord blood at birth. However, only a small amount of blood can be retrieved from the umbilical cord, so this type of transplant is generally reserved for children and small adults.
- Bone marrow and peripheral blood stem cell transplants. American Cancer Society. http://www.cancer.org/docroot/ETO/eto_1_3_Bone_Marrow.asp. Accessed Feb. 18, 2009.
- Bone marrow transplantation and peripheral blood stem cell transplantation. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/Therapy/bone-marrow-transplant. Accessed Feb. 19, 2009.
- What are stem cells? American Cancer Society. http://www.cancer.org/docroot/ETO/content/ETO_1_4X_What_Are_Stem_Cells.asp?sitearea=ETO. Accessed Feb. 18, 2009.
- Filgrastim (granulocyte colony stimulating factor; G-CSF). Facts & Comparisons 4.0. http://www.factsandcomparisons.com. Accessed Feb. 18, 2009.
- HLA matching: Finding the best donor or cord blood unit. Be the Match Registry. Accessed May 4, 2009.
- Gronseth MJ (expert opinion). Mayo Clinic, Rochester, Minn. May 1, 2009.
