BRCA gene test for breast cancer

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What you can expect

By Mayo Clinic staff

The BRCA gene test is a blood test. A doctor, nurse or medical technician inserts a needle into a vein, usually in your arm, to draw the blood sample needed for testing. Your blood sample then goes to a laboratory for DNA analysis. It takes about three to four weeks before test results are available. In most cases, you meet with your genetic counselor again to learn your test results, discuss their implications and go over your options.

References
  1. Peshkin BN, et al. Patient information: Genetic testing for breast and ovarian cancer. http://www.uptodate.com/home/index.html. Accessed Oct. 17, 2008.
  2. U.S. Preventive Services Task Force. Genetic risk assessment and BRCA mutation testing for breast and ovarian cancer susceptibility: Recommendation statement. Annals of Internal Medicine. 2005;143:355.
  3. The American College of Obstetricians and Gynecologists. Elective and risk-reducing salpingo-oophorectomy. Obstetrics & Gynecology. 2008;111:231.
  4. Genetic testing for BRCA1 and BRCA2: It's your choice. National Cancer Institute. http://www.cancer.gov/cancertopics/factsheet/Risk/BRCA. Accessed Oct. 22, 2008.
  5. Cancer facts and figures 2008. American Cancer Society. http://www.cancer.org/downloads/STT/2008CAFFfinalsecured.pdf. Accessed Oct. 17, 2008.
  6. Brown KL, et al. Genetic counseling for breast cancer risk: General concepts, challenging themes and future directions. Breast Disease. 2006-2007;27:69.
  7. Lindor NM, et al. Concise handbook of familial cancer susceptibility syndromes - Second edition. Journal of the National Cancer Institute. Monographs. 2008;38:1.
  8. Rebbeck TR, et al. Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: The PROSE study group. Journal of Clinical Oncology. 2004;22:1055.
  9. Finch A, et al. Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women. Journal of the American Medical Association. 2006;296:185.

MY00322

Dec. 3, 2008

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