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Prevention

By Mayo Clinic staff

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Illustration demonstrating breast self-exam
Breast self-examination

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Breast cancer prevention for women with an average risk
Making changes in your daily life may help reduce your risk of breast cancer. Try to:

  • Ask your doctor about breast cancer screening. Ask your doctor at what age you should begin breast cancer screening exams and tests, such as clinical breast exams and mammograms. Talk to your doctor about the benefits and risks of screening. Together you can decide what breast cancer screening strategies are right for you.
  • Become familiar with your breasts through breast self-exams. Ask your doctor to show you how to do a breast self-exam to check for any lumps or other unusual signs in your breasts. A breast self-exam can't prevent breast cancer, but it may help you to better understand the normal changes that your breasts undergo and identify any unusual signs and symptoms.
  • Drink alcohol in moderation, if at all. Limit the amount of alcohol you drink to less than one drink a day, if you choose to drink.
  • Exercise most days of the week. Aim for at least 30 minutes of exercise on most days of the week. If you haven't been active lately, ask your doctor whether it's OK and start slowly.
  • Limit postmenopausal hormone therapy. Combination hormone therapy may increase the risk of breast cancer. Talk with your doctor about the benefits and risks of hormone therapy. Some women experience bothersome signs and symptoms during menopause and, for these women, the increased risk of breast cancer may be acceptable in order to relieve menopause signs and symptoms. To reduce the risk of breast cancer, use the lowest dose of hormone therapy possible for the shortest amount of time.
  • Maintain a healthy weight. If your current weight is healthy, work to maintain that weight. If you need to lose weight, ask your doctor about healthy strategies to accomplish this. Reduce the number of calories you eat each day and slowly increase the amount of exercise. Aim to lose weight slowly — about 1 or 2 pounds a week.

Breast cancer prevention for women with a high risk
If your doctor has assessed your family history and other factors and determined that you may have an increased risk of breast cancer, options to reduce your risk include:

  • Preventive medications (chemoprevention). Estrogen-blocking medications help reduce the risk of breast cancer. Options include tamoxifen and raloxifene (Evista). These medications carry a risk of side effects, so doctors reserve these medications for women who have a very high risk of breast cancer.
  • Preventive surgery. Women with a very high risk of breast cancer may choose to have their healthy breasts surgically removed (prophylactic mastectomy). They may also choose to have their healthy ovaries removed (prophylactic oophorectomy) to reduce the risk of both breast cancer and ovarian cancer.
References
  1. Cancer facts & figures 2008. American Cancer Society. http://www.cancer.org/downloads/STT/2008CAFFfinalsecured.pdf. Accessed April 15, 2009.
  2. What you need to know about breast cancer. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/breast/allpages/print. Accessed March 30, 2009.
  3. Abeloff MD, et al. Cancer of the breast. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:1875.
  4. Breast cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/breast.pdf. Accessed March 30, 2009.
  5. Breast cancer prevention (PDQ): Patient version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/prevention/breast/patient/allpages/print. Accessed March 30, 2009.
  6. Questions to ask yourself and your doctor. Breast Cancer Network of Strength. http://www.networkofstrength.org/support/selfcare/questions.php. Accessed April 1, 2009.
  7. Hulvat MC, et al. Multidisciplinary care of patients with breast cancer. Surgical Clinics of North America. 2009;89:133.
  8. Avastin (prescribing information). San Francisco, Calif: Genentech; 2008. http://www.fda.gov/cder/foi/label/2008/125085s145lbl.pdf. Accessed April 15, 2009.
  9. Tykerb (prescribing information). Research Triangle Park, N.C.: GlaxoSmithKline; 2007. http://www.fda.gov/cder/foi/label/2008/022059s004lbl.pdf. Accessed April 15, 2009.
  10. Found 1084 studies with search of: breast cancer | Open studies | Interventional studies. ClinicalTrials.gov. http://www.clinicaltrials.gov/ct2/results?term=breast+cancer&recr=Open&rslt=&type=Intr&cond=&intr=&outc=&lead=&spons=&id=&state1=&cntry1=&state2=&cntry2=&state3=&cntry3=&locn=&rcv_s=&rcv_e=&lup_s=&lup_e=. Accessed April 15, 2009.
  11. Gnant M, et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. The New England Journal of Medicine. 2009;360:679.
  12. Bardwell WA, et al. Breast cancer and fatigue. Sleep Medicine Clinics. 2008;3:61.
  13. Cancer-related fatigue. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/fatigue.pdf. Accessed April 15, 2009.
  14. Breast cancer. Cancer.Net. http://www.cancer.net/patient/Cancer+Types/Breast+Cancer. Accessed April 15, 2009.

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Nov. 19, 2009

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