Carotid artery disease

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Complications

By Mayo Clinic staff

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Illustration of ischemic stroke Ischemic stroke

The most serious complication of carotid artery disease is stroke. There are different ways carotid artery disease can increase your risk of stroke:

  • Reduced blood flow. A carotid artery may become so narrowed by atherosclerosis that not enough blood is able to reach portions of your brain.
  • Ruptured plaque. A piece of a plaque may break off and flow to smaller arteries in your brain (cerebral arteries). The fragment may get stuck in one of these smaller arteries, creating a blockage that cuts off blood supply to the area of the brain that the cerebral artery serves (stroke).
  • Blood clot blockage. Some plaques are prone to cracking and forming irregular surfaces on the artery wall. When this happens, your body reacts as if to an injury and sends platelets — blood cells that help the clotting process — to the area. A large blood clot may develop in this manner and block or slow the flow of blood through a carotid or cerebral artery, causing a stroke.

A stroke can leave you with permanent brain damage and muscle weakness. In severe cases, it can be fatal.

Preparing for your appointment Risk factors
References
  1. Lee JT, et al. Peripheral arterial disease. In: Rakel RE, et al. Conn's Current Therapy 2008. 60th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/151488178-7/866918859/1621/197.html#4-u1.0-B978-1-4160-4435-2..50101-1_1467. Accessed July 23, 2009.
  2. Riles TS, et al. Cerebrovascular disease. In: Townsend CM, et al. Sabiston Textbook of Surgery. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/151488178-3/866914256/1565/622.html#4-u1.0-B978-1-4160-3675-3..50068-X--cesec4_3762. Accessed July 23, 2009.
  3. Schwartz JB, et al. Vascular disease. In: Libby P, et al., eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2007.http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-1-4160-4106-1..50078-9--cesec28&uniq=151488178&isbn=978-1-4160-4106-1&sid=866915121#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-1-4160-4106-1..50078-9--cesec95%3Bfrom%3Dtoc%3Btype%3DbookPage%3Bisbn%3D978-1-4160-4106-1. Accessed July 23, 2009.
  4. Carotid artery disease. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/catd/catd_whatis.html. Accessed July 23, 2009.
  5. Carotid artery disease, stroke, transient ischemic attacks (TIAs). Society for Vascular Surgery. http://www.vascularweb.org/patients/NorthPoint/Carotid_Artery_Disease.html. Accessed July 23, 2009.
  6. Furie KL, et al. Secondary prevention of stroke: Risk factor reduction. http://www.uptodate.com/home/index.html. Accessed July 23, 2009.
  7. Angioplasty and vascular stenting. Radiological Society of North America. http://www.radiologyinfo.org/en/info.cfm?pg=angioplasty. Accessed Aug. 28, 2009.
  8. Questions and answers about carotid endarterectomy. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/stroke/carotid_endarterectomy_backgrounder.htm. Accessed Aug. 12, 2009.
  9. Greelish JP, et al. Carotid angioplasty and stenting. http://www.uptodate.com/home/index.html. Accessed July 23, 2009.
  10. Greelish JP, et al. Carotid endarterectomy: Preoperative evaluation; surgical technique; and complications. http://www.uptodate.com/home/index.html. Accessed July 23, 2009.
  11. Sodium. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4708. Accessed July 23, 2009.
  12. Stop smoking: Resources and tools for quitting. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=3038010. Accessed July 23, 2009.
  13. Rundek T, et al. Risk factor management to prevent first stroke. Neurologic Clinics.2008;26:1007.

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Oct. 1, 2009

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