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By Mayo Clinic staffChelation therapy has been used as a treatment for mercury and lead poisoning for years. More recently, some doctors and alternative medicine practitioners have recommended chelation therapy to treat heart disease and stroke. But other doctors are worried that chelation therapy doesn't work, or worse, could be dangerous. The American Heart Association doesn't recommend chelation therapy as a treatment for heart disease, and the Food and Drug Administration hasn't approved chelation therapy for use as a heart disease treatment.