Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Symptoms

By Mayo Clinic staff

Signs and symptoms of chemo brain may include:

  • Being unusually disorganized
  • Confusion
  • Difficulty concentrating
  • Difficulty finding the right word
  • Difficulty learning new skills
  • Difficulty multitasking
  • Fatigue
  • Feeling of mental fogginess
  • Short attention span
  • Short-term memory problems
  • Taking longer than usual to complete routine tasks
  • Trouble with verbal memory, such as remembering a conversation
  • Trouble with visual memory, such as recalling an image or list of words

Signs and symptoms of cognitive or memory problems vary from person to person and are typically temporary, often subsiding within two years of completion of cancer treatment.

When to see a doctor
If you experience troubling memory or thinking problems, make an appointment with your doctor. Keep a journal of your signs and symptoms so that your doctor can better understand how your memory problems are affecting your everyday life.

References
  1. Vardy J, et al. Cognitive function after chemotherapy in adults with solid tumors. Critical Reviews in Oncology/Hematology. 2007;63(3):183-202.
  2. Vardy J, et al. Evaluation of cognitive function associated with chemotherapy: A review of published studies and recommendations for future research. Journal of Clinical Oncology. 2007;25(17):2455-2463.
  3. Definition of a neuropsychologist. National Academy of Neuropsychology. http://www.nanonline.org/NAN/PAIC/PositionPapers/DefinitionofaNeuropsychologist.aspx. Accessed Aug. 28, 2008.
  4. Vardy J, et al. Cancer and cancer-therapy related cognitive dysfunction: An international perspective from the Venice cognitive workshop. Annals of Oncology. 2008;19(4):623-629.
  5. Taillibert S, et al. Chemobrain: Is systemic chemotherapy neurotoxic? Current Opinion in Oncology. 2007;19(6):623-627.
  6. Hurria A, et al. Renaming "chemobrain." Cancer Investigation. 2007;25(6):373-377.
  7. Cognitive problems after chemotherapy. CancerCare. http://www.cancercare.org/pdf/fact_sheets/fs_chemobrain_cognitive.pdf. Accessed Aug. 28, 2008.
  8. Doctor, can we talk about chemobrain? CancerCare. http://www.cancercare.org/pdf/fact_sheets/fs_chemobrain_doctor_talk.pdf. Accessed Aug. 28, 2008.
  9. Ways to improve concentration: Three key steps. CancerCare. http://www.cancercare.org/pdf/fact_sheets/fs_chemobrain_concentration.pdf. Accessed Aug. 28, 2008.
  10. Combating chemobrain: Keeping your memory sharp. CancerCare. http://www.cancercare.org/pdf/fact_sheets/fs_chemobrain_memory.pdf. Accessed Aug. 28, 2008.
  11. Cognitive changes. Lance Armstrong Foundation. http://www.livestrong.org/site/c.khLXK1PxHmF/b.2660693/k.2D96/Physical_Effects_Cognitive_Changes.htm. Accessed Aug. 25, 2008.
  12. Cognitive problems. Cancer.Net. http://www.asco.org/patient/Diagnosis+and+Treatment/Treating+Cancer/Managing+Side+Effects/Cognitive+Problems. Accessed Aug. 25, 2008.
  13. Ginkgo. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Aug. 28, 2008.
  14. Vitamin E. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed Aug. 28, 2008.
  15. Brown PD, et al. Neurocognitive effects. In: DeVita TJ, et al. Cancer Principles & Practice of Oncology. 8th ed. Philadelphia, Pa.: Lippincott Williams & Wilkins; 2008:2751-2756.
  16. Ganz PA. Cancer Survivorship. New York, N.Y.: Springer; 2007:59-60.
  17. Ferguson RJ, et al. Management of chemotherapy-related cognitive dysfunction. In: Feuerstein M. Handbook of Cancer Survivorship. New York, NY: Springer; 2007:287-301.
  18. Moynihan TJ (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 9, 2008.
  19. Creagan ET (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 11, 2008.

DS01109

Oct. 11, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger