- With Mayo Clinic medical oncologist
Timothy Moynihan, M.D.
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Timothy Moynihan, M.D.
Timothy Moynihan, M.D.
"As a practicing medical oncologist, I meet with patients and families every day to help manage their course through this disease called cancer. This experience provides unique insight into the needs of cancer patients, their families and loved ones and brings into sharp focus the need for reliable information to be readily available in terms that can be easily understood." — Dr. Timothy Moynihan
Dr. Timothy Moynihan believes that providing consumers accurate, timely information on the broad, complex topic of cancer is the biggest challenge facing medical Web sites. As the guiding force behind our cancer coverage, he makes sure Mayo Clinic meets the test.
Dr. Moynihan, born in Las Vegas, N.M., but raised in Denver, is a consultant in medical oncology at Mayo Clinic and an associate professor at Mayo Clinic College of Medicine. He is board certified in internal medicine, medical oncology, and hospice and palliative care medicine. He did his medical oncology training at Johns Hopkins Hospital in Baltimore, and then went on to the University of Minnesota and St. Paul Regions Medical Center in St. Paul, Minn., for seven years before moving to Mayo Clinic in 1999. Dr. Moynihan is director of the palliative care program at Mayo Clinic and associate medical director of the Mayo Clinic hospice.
Dr. Moynihan currently serves as the education chair for the Department of Medical Oncology and fellowship program director. Four times he has been selected as Teacher of the Year in medical oncology and elected to the Teacher of the Year Hall of Fame. Past honors include distinguished clinical teacher at the University of Minnesota Medical School, best internist at the Medical College of Wisconsin and recipient of The Upjohn Achievement Award for Excellence in Medicine. He serves on several national committees for the American Society of Clinical Oncology.
"The Internet provides a ready source of information on a wide range of topics of interest to those affected by cancer," Dr. Moynihan says. "The difficulty is trying to decide which sites provide reputable information and which information is relevant to each individual patient. The long history and tradition of excellence associated with Mayo Clinic assures you that information provided will be reliable, up-to-date and comprehensive."
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Question
Chemotherapy side effects: A cause of heart disease?
Can chemotherapy increase the risk of heart disease?
Answer
from Timothy Moynihan, M.D.
Some chemotherapy drugs may increase the risk of heart disease, especially weakness of the heart muscle (cardiomyopathy). Certain types of chemotherapy also increase the risk of heart attack, especially during infusion of the medication. Fortunately, heart disease associated with chemotherapy is relatively rare — and not all chemotherapy drugs carry the potential side effect of heart damage.
It's important to note that some newer anti-cancer treatments — such as trastuzumab (Herceptin) for breast cancer — may cause heart damage as well, although the effect is often reversible.
If your doctor is considering using a chemotherapy drug that may affect your heart, he or she may test your heart function before starting treatment. During treatment, you may need periodic heart monitoring as well. If you have a pre-existing heart condition, such as cardiomyopathy, your doctor may suggest a different type of chemotherapy.
Generally, the risk of heart disease associated with certain chemotherapy drugs increases with the total lifetime amount of the drug you receive. To minimize the risk of heart damage, your doctor will carefully monitor the amount of each type of chemotherapy drug you receive. If you experience chest pain or other symptoms of a heart attack during chemotherapy, report it immediately to your health care team.
In addition, some cancers require radiation therapy. If the area of your body receiving radiation includes your heart, you have an increased risk of cardiomyopathy, coronary artery disease and heart attack. The combination of radiation and chemotherapy can further increase your risk of heart damage. However, your doctor can take steps to reduce these risks as much as possible.
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