Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedCauses
By Mayo Clinic staffThe causes of chronic daily headaches are not well understood. Some may be caused by various underlying diseases or conditions, including:
- Inflammation or other problems with the blood vessels in and around the brain
- Infections, such as meningitis
- Intracranial pressure that's either too high or too low
- Pinched nerves in the neck
- Brain tumor
- Traumatic brain injury
In most cases, however, chronic daily headaches don't have an underlying physical cause. They may occur if you develop a heightened response to pain signals or if the part of your brain that suppresses pain signals isn't working properly.
Many people who have chronic daily headaches are actually experiencing a rebound effect from taking pain medication too frequently. If you are taking pain medications — even over-the-counter analgesics — more than two days a week, you're at risk of developing rebound headaches.