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Risk factors

By Mayo Clinic staff

The risk factors for claudication are the same as those for developing atherosclerosis, including:

  • Smoking
  • Total blood cholesterol over 240 mg/dL (6.2 mmol/L)
  • High blood pressure
  • Obesity (a body mass index over 30)
  • Diabetes
  • Age over 70 years
  • Age over 50 years if you also smoke or have diabetes
  • A family history of atherosclerosis, peripheral artery disease or claudication
Complications Causes
References
  1. Mohler ER. Clinical features, diagnosis, and natural history of lower extremity
  2. peripheral arterial disease. http://www.uptodate.com/home/index.html. Accessed Nov. 3, 2009.
  3. Arm artery disease. Society for Vascular Surgery. http://www.vascularweb.org/patients/NorthPoint/Arm_Artery_Disease.html. Accessed Nov. 3, 2009.
  4. PAD — Peripheral arterial disease and claudication. Society for Vascular Surgery. http://www.vascularweb.org/patients/NorthPoint/Claudication.html. Accessed Nov. 3, 2009.
  5. Peripheral artery disease. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec07/ch080/ch080f.html. Accessed Nov. 3, 2009.
  6. Hiatt WR, et al. Pathophysiology of intermittent claudication. In: Creager MA, et al. Vascular Medicine: A Companion to Braunwald's Heart Disease. Philadelphia, Pa.; Saunders Elsevier: 2006. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-7216-0284-4..50021-X&uniq=168838833&isbn=978-0-7216-0284-4&sid=911701564#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-7216-0284-4..50001-4%3Bfrom%3Dtoc%3Btype%3DbookPage%3Bisbn%3D978-0-7216-0284-4. Accessed Nov. 3, 2009.
  7. Murphy TP, et al. The CLEVER (Claudication: Exercise vs. endoluminal revascularization study): Rationale and methods. Journal of Vascular Surgery. 2008;47:1356
  8. Wennberg PW, et al. Diagnosis and management of diseases of the peripheral arteries and veins. In: Fuster V, et al. In: Hurst's The Heart. 12th ed. New York, N.Y.; McGraw-Hill Medical: 2007. http://www.accessmedicine.com/content.aspx?aID=3076431. Accessed Nov. 3, 2009.
  9. Michel T. Treatment of myocardial ischemia. In: Brunton LL, et al. Goodman and Gilman's The Pharmacological Basis of Therapeutics. 11th edition. New York, N.Y.; McGraw-Hill Medical: 2006. http://www.accessmedicine.com/content.aspx?aID=944592. Accessed Nov. 3, 2009.
  10. Gey DC, et al. Management of peripheral arterial disease. American Family Physician. 2004;69:525.
  11. Grogan M (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 13, 2009.
  12. Anderson CA (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 5, 2009.

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Jan. 5, 2010

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