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Definition
By Mayo Clinic staffComplex regional pain syndrome (CRPS) is an uncommon, chronic condition that usually affects your arm or leg. Rarely, complex regional pain syndrome can affect other parts of your body.
Complex regional pain syndrome is marked by intense burning or aching pain. You may also experience swelling, skin discoloration, altered temperature, abnormal sweating and hypersensitivity in the affected area.
The cause of complex regional pain syndrome isn't clearly understood, though it often follows an illness or injury. Treatment for complex regional pain syndrome is most effective when started early. In such cases, dramatic improvement and even remission are possible.
- Sheon RP, et al. Etiology, clinical manifestations, and diagnosis of complex regional pain syndrome in adults. http://www.uptodate.com/home/index.html. Accessed Jan. 9, 2009.
- Sheon RP, et al. Prevention and management of complex regional pain syndrome in adults. http://www.uptodate.com/home/index.html. Accessed Jan. 9, 2009.
- Complex regional pain syndrome fact sheet. National Institute of Neurological Disorders and Stroke. Accessed Jan. 8, 2009.
- Neuropathic pain. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec16/ch209/ch209c.html#sec16-ch209-ch209c-285. Accessed Feb. 5, 2009.
- Sandroni P (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 30, 2009.
