Depersonalization disorder

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Causes

By Mayo Clinic staff

Feeling of depersonalization may:

  • Begin with no apparent trigger
  • Start after a life-threatening event, such as an accident or assault
  • Be triggered by fear of having another depersonalization experience

With depersonalization disorder, feelings of depersonalization aren't directly caused by drugs, alcohol or a medical condition. However, depersonalization may be triggered by stress or trauma, and it often occurs along with other mental health conditions such as anxiety, depression or schizophrenia. In some cases, it starts suddenly without an apparent cause.

While the exact cause of depersonalization disorder isn't well understood, it appears to be linked to the balance of certain brain chemicals (neurotransmitters).

References
  1. Depersonalization.disorder. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed June 11, 2009.
  2. Simeon D. Depersonalization disorder: A contemporary overview. CNS Drugs. 2004;18:343.
  3. Depersonalization disorder. In: Moore DP, et al. Handbook of Medical Psychiatry. 2nd ed. Philadelphia, Pa.: Mosby; 2004. http://www.mdconsult.com/das/book/body/147320988-3/0/1243/99.html?tocnode=52436700&fromURL=99.html#4-u1.0-B0-323-02911-6..50099-3_926. Accessed June 11, 2009.

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July 11, 2009

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