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Definition

By Mayo Clinic staff

Down syndrome is a genetic disorder that causes lifelong mental retardation, developmental delays and other problems. Down syndrome varies in severity, so developmental problems range from moderate to serious.

Down syndrome is the most common genetic cause of severe learning disabilities in children, occurring in one in every 700 to 800 infants.

Increased understanding of Down syndrome and early interventions make a big difference in the lives of both children and adults with Down syndrome.

References
  1. Down syndrome. National Institute of Child Health and Human Development. http://www.nichd.nih.gov/health/topics/down_syndrome.cfm. Accessed Jan. 9, 2009.
  2. Barss V, et al. Overview of prenatal screening and diagnosis of Down syndrome. http://www.uptodate.com/home/index.html. Accessed Jan. 9, 2009.
  3. Down syndrome Q & A. National Down Syndrome Society. http://www.ndss.org/index.php?option=com_content&view=article&id=55:down-syndrome-q-a-a&catid=35:about-down-syndrome&Itemid=75. Accessed Jan. 20, 2009.
  4. What causes Down syndrome? National Down Syndrome Society. http://www.ndss.org/index.php?option=com_content&task=category§ionid=23&id=60&Itemid=234. Accessed Jan. 20, 2009.
  5. Genetic conditions: Down syndrome. Genetics Home Reference. http://ghr.nlm.nih.gov/condition=downsyndrome. Accessed Jan. 9, 2009.
  6. Facts about Down syndrome. National Institute of Child Health and Human Development. http://www.nichd.nih.gov/publications/pubs/downsyndrome.cfm. Accessed Jan. 20, 2009.
  7. Canick JA, et al. Second trimester maternal serum screening for Down syndrome. http://www.uptodate.com/home/index.html. Accessed Jan. 9, 2009.

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April 7, 2009

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