Nafarelin (Nasal Route)

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Nafarelin (Nasal Route)

Drug Information provided by: Micromedex

US Brand Names

  • Synarel

Description

Nafarelin is a hormone similar to the one normally released from the hypothalamus gland in the brain. It is used in the treatment of:

  • Endometriosis, a painful condition caused by extra tissue similar to the lining of the uterus growing inside and outside of the uterus.
  • Central precocious puberty (CPP), puberty developing too early in boys and girls.

Nafarelin works by decreasing the amount of estrogen and testosterone in the blood.

When given regularly to boys and girls, this medicine helps to prevent them from continuing to develop the sexual features associated with puberty, slowing down the development of breasts in girls and the development of genital areas in boys and girls. This medicine delays puberty in a child only as long as the child continues to take it.

Nafarelin prevents the growth of tissue associated with endometriosis in adult women during treatment and for 6 months after treatment is discontinued. Reducing the amount of estrogen in the body is one way of treating endometriosis.

Suppressing estrogen can thin the bones or slow their growth. This is a problem for adult women whose bones are no longer growing like the bones of children. Slowing the growth of bones is a positive effect for girls and boys whose bones grow too fast when puberty begins too early. This is why nafarelin is used only for up to 6 months in adult women treated for endometriosis, but often is used for a longer time in girls and boys with pubertal problems. Boys and girls may benefit by adding inches to their adult height when nafarelin causes their bones to grow at a proper rate.

Nafarelin is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Spray
Before Using

DR600969

Portions of this document last updated:

Nov. 1, 2009

Source: Drug Information provided by: Micromedex

Copyright © 2010 Thomson Healthcare Inc. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.


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