Mayo Clinic Health Manager
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Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common- Abnormal or decreased touch sensation
- Bleeding after defecation
- Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at site
- Bloating or swelling of face, arms, hands, lower legs, or feet
- Blood in urine
- Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
- Changes in skin color
- Cold flu-like symptoms
- Cold hands and feet
- Confusion
- Constipation
- Cough or hoarseness
- Darkened urine
- Decreased urination
- Diarrhea
- Difficult urination
- Difficulty in moving
- Dizziness
- Dry mouth
- Fainting or loss of consciousness
- Fast heartbeat
- Fast or irregular breathing
- Feeling unusually cold
- Fever or chills
- Frequent or painful urination
- Full or bloated feeling
- General feeling of discomfort or illness
- Headache
- Increase in heart rate
- Indigestion
- Itching
- Joint pain
- Light-colored stools
- Lightheadedness
- Loss of appetite
- Lower back or side pain
- Muscle aching or cramping
- Muscle pain or stiffness
- Nausea
- Pain
- Pain or burning while urinating
- Pain, redness, or swelling in arm or leg
- Pains in stomach, side, or abdomen, possibly radiating to the back
- Pressure in the stomach
- Rapid, shallow breathing
- Rapid weight gain
- Rectal bleeding
- Runny nose
- Shivering
- Skin rash
- Sneezing
- Sore mouth or tongue
- Sore throat
- Stomach bloating, burning, cramping, or pain
- Sudden decrease in amount of urine
- Sunken eyes
- Sweating
- Swelling of abdominal or stomach area
- Swelling of eyes or eyelids
- Swelling or puffiness of face
- Swollen joints
- Thirst
- Tightness in chest and/or wheezing
- Tingling of hands or feet
- Trouble in breathing
- Trouble sleeping
- Uncomfortable swelling around anus
- Unpleasant breath odor
- Unusual tiredness or weakness
- Unusual weight gain or loss
- Vomiting
- Vomiting of blood
- White patches in mouth, tongue, or throat
- Wrinkled skin
- Yellow eyes or skin
- Bone or skeletal pain
- Burning, numbness, pain, or tingling in all fingers except smallest finger
- Chest pain
- Depressed mood
- Dry skin and hair
- Feeling cold
- Hair loss
- Hoarseness or husky voice
- Slowed heartbeat
- Swelling of ankles
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of Overdose- Anxiety
- Blurred vision
- Changes in vision
- Cold sweats
- Coma
- Cool, pale skin
- Decrease in amount of urine
- Depression
- Excessive sweating
- Extreme weakness
- Fatigue
- Flushed, dry skin
- Frequent urination
- Fruit-like breath odor
- Increase in hands and feet size
- Increased hunger
- Increased thirst
- Increased urination
- Increased volume of pale, diluted urine
- Nervousness
- Nightmares
- Noisy, rattling breathing
- Pain in extremities
- Seizures
- Shakiness
- Shortness of breath
- Slurred speech
- Stop in menstruation
- Swelling of fingers or hands
- Troubled breathing at rest
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common- Body aches or pain
- Breast pain
- Change in the color, amount, or odor of vaginal discharge
- Congestion
- Difficulty having a bowel movement (stool)
- Discoloration of fingernails or toenails
- Dryness or soreness of throat
- Excess air or gas in stomach or intestines
- Frequent urge to defecate
- Increased sweating
- Passing gas
- Rash
- Sneezing
- Straining while passing stool
- Stuffy nose
- Tender, swollen glands in neck
- Trouble in swallowing
- Voice changes
- Discouragement
- Feeling sad or empty
- Irritability
- Lack of appetite
- Loss of interest or pleasure
- Sleeplessness
- Tiredness
- Trouble concentrating
- Unable to sleep
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.