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By Mayo Clinic staffDupuytren's contracture is an uncommon hand deformity in which the connective tissue under the skin of your palm contracts and toughens over time.
Knots of tissue form under the skin, eventually forming a thick cord that can pull one or more of your fingers into a bent position. Once this occurs, the fingers affected by Dupuytren's contracture bend normally but they can't be straightened completely, making it difficult to use your hand. Dupuytren's contracture can complicate everyday activities such as placing your hands in your pockets, putting on gloves or shaking hands.
Dupuytren's contracture is rarely painful, though sometimes the bumps of tissue on your palm can be sensitive to touch. Various treatments are available for Dupuytren's contracture to slow its progression and relieve your symptoms.