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Risk factors
By Mayo Clinic staffRisk factors for emphysema include:
- Smoking. Emphysema is most likely to develop in cigarette smokers, but cigar and pipe smokers also are susceptible, and the risk for all types of smokers increases with the number of years and amount of tobacco smoked.
- Age. Although the lung damage that occurs in emphysema develops gradually, most people with tobacco-related emphysema begin to experience symptoms of the disease between the ages of 40 and 60.
- Exposure to secondhand smoke. Secondhand smoke, also known as passive or environmental tobacco smoke, is smoke that you inadvertently inhale from someone else's cigarette, pipe or cigar. Being around secondhand smoke increases your risk of emphysema.
- Occupational exposure to fumes or dust. If you breathe fumes from certain chemicals or dust from grain, cotton, wood or mining products, you're more likely to develop emphysema. This risk is even greater if you smoke.
- Exposure to indoor and outdoor pollution. Breathing indoor pollutants, such as fumes from heating fuel, as well as outdoor pollutants — car exhaust, for instance — increases your risk of emphysema.
- HIV infection. Smokers living with HIV are at greater risk of emphysema than are smokers who don't have HIV infection.
- Connective tissue disorders. Some conditions that affect connective tissue — the fibers that provide the framework and support for your body — are associated with emphysema. These conditions include cutis laxa, a rare disease that causes premature aging, and Marfan syndrome, a disorder that affects many different organs, especially the heart, eyes, skeleton and lungs.
References
- Emphysema. American Lung Association. http://www.lungusa.org/site/apps/nlnet/content3.aspx?c=dvLUK9O0E&b=2060053&content_id={39330D56-C0E9-4D08-B98F-18EA7B3C410B}¬oc=1. Accessed March 4, 2009.
- Chronic obstructive pulmonary disease (COPD) fact sheet. American Lung Association. http://www.lungusa.org/site/apps/nlnet/content3.aspx?c=dvLUK9O0E&b=2058829&content_id={EE451F66-996B-4C23-874D-BF66586196FF}¬oc=1. Accessed March 4, 2009.
- What is COPD? National Heart Lung and Blood Institute, National Institutes of Health. http://www.nhlbi.nih.gov/health/dci/Diseases/Copd/Copd_WhatIs.html. Accessed March 4, 2009.
- Celli BR. Update on the management of COPD. CHEST. 2008;133:1451.
- Bruce ML, et al. COPD: Your role in early detection. The Nurse Practitioner Journal. 2007;32:25.
- Corbridge SJ, et al. Chronic obstructive pulmonary disease. AAOHN Journal. 2007;55:181.
- Rennard SI. Chronic obstructive pulmonary disease: Definition, clinical manifestations, diagnosis, and staging. http://www.uptodate.com. Accessed March 4, 2009.
- Weiss ST. Chronic obstructive pulmonary disease: Risk factors and risk reduction. http://www.uptodate.com. Accessed March 4, 2009.
- Ferguson GT et al, Management of stable chronic obstructive pulmonary disease. http://www.uptodate.com. Accessed March 4, 2009.
- Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Global initiative for Chronic Obstructive Lung Disease. Medical Communications Resources, Inc. Accessed March 20, 2009.
