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Risk factors
By Mayo Clinic staffIt's thought that chronic irritation of your esophagus may contribute to the DNA changes that cause esophageal cancer. Factors that cause irritation in the cells of your esophagus and increase your risk of esophageal cancer include:
- Alcohol
- Bile reflux
- Chewing tobacco
- Difficulty swallowing caused by an esophageal sphincter that won't relax (achalasia)
- Drinking very hot liquids
- Eating a diet low in fruits and vegetables
- Eating foods preserved in lye
- Gastroesophageal reflux disease (GERD)
- Obesity
- Precancerous changes in the cells of the esophagus (Barrett's esophagus)
- Radiation treatment to the chest or upper abdomen
- Smoking
References
- Kleinberg LR, et al. Cancer of the esophagus. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:1399.
- Esophageal cancer. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/esophageal.pdf. Accessed March 9, 2009.
- Esophageal cancer treatment (PDQ) health professional version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/esophageal/healthprofessional/allpages. Accessed March 9, 2009.
- Esophageal cancer screening (PDQ) health professional version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/screening/esophageal/healthprofessional/allpages. Accessed March 9, 2009.
- Questions to ask the doctor. Cancer.Net. http://www.cancer.net/patient/Cancer+Types/Esophageal+Cancer. Accessed March 10, 2009.
- Eating hints for cancer patients: Before, during and after treatment. National Cancer Institute. http://www.cancer.gov/cancertopics/eatinghints/allpages/print. Accessed March 12, 2009.
- Adult cancer pain. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/pain.pdf. Accessed March 12, 2009.
- Esophageal cancer prevention (PDQ) health professional version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/prevention/esophageal/healthprofessional/allpages. Accessed March 9, 2009.
