Factor V Leiden

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Definition

Factor V Leiden is a common inherited genetic disorder in which your blood has an increased tendency to form clots (thrombophilia), usually in your veins.

Although blood clots can form at any age, for most people the increased risk of clotting doesn't begin until adulthood. Most people with factor V Leiden never develop abnormal clots. However, some people with factor V Leiden develop clots that lead to long-term health problems or are life-threatening.

Both men and women can have factor V Leiden, but women may have an increased tendency to develop blood clots during pregnancy or when taking the hormone estrogen.

If you have factor V Leiden, medications can lessen your risk of developing blood clots and help you avoid potentially serious complications.

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Symptoms