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Causes
By Mayo Clinic staffIn some people with Fuchs' dystrophy, the cause is unknown. However, for many people it's inherited as an autosomal dominant familial condition, meaning that about half of an affected person's children also will have the disease. The extent to which relatives experience signs and symptoms may vary. For instance, a parent with a mild case and few symptoms could have a child with a severe case and numerous vision problems.
- Afshari NA, et al. Clinical study of Fuchs corneal endothelial dystrophy leading to penetrating keratoplasty. Archives of Ophthalmology. 2006;124:777.
- Biswell R. Cornea. In: Riordan-Eva P, et al. Vaughan & Asbury's General Ophthalmology, 17th edition. Columbus, Ohio: McGraw-Hill Companies; 2008.
- Facts about the cornea and corneal disease. National Eye Institute. http://www.nei.nih.gov/health/cornealdisease. Accessed June 18, 2009.
- Genetic and rare diseases information center. Office of Rare Diseases Research. http://rarediseases.info.nih.gov/GARD/QnA.aspx?PageID=4&CaseID=23860&DiseaseID=9678. Accessed June 18, 2009.
- Visiting your doctor. The Corneal Dystrophy Foundation. http://www.fuchs-dystrophy.com/index.html. Accessed June 18, 2009.
- Coping tips. The Corneal Dystrophy Foundation. http://www.fuchs-dystrophy.com/html/tips_for_you_to_alleviate_symp.html. Accessed June 18, 2009.
- Cornea conditions and updates. Cornea Research Foundation of America. http://www.cornea.org/crf_cornea.html. Accessed June 26, 2009.
- Artificial cornea. Cornea Research Foundation of America. http://www.cornea.org/study_cornea.html. Accessed June 26, 2009.
- 9. Current Fuchs' corneal dystrophy studies. The Corneal Dystrophy Foundation. http://www.cornealdystrophyfoundation.org/html/studies.html. Accessed June 26, 2009.
- Robertson DM (expert opinion). Mayo Clinic, Rochester, Minn. July 1, 2009.
