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Complications

By Mayo Clinic staff

Complications of gallstones may include:

  • Inflammation of the gallbladder. A gallstone that becomes lodged in the neck of the gallbladder can cause inflammation of the gallbladder (cholecystitis). Cholecystitis can cause severe pain and fever.
  • Blockage of the common bile duct. Gallstones can block the tubes (ducts) through which bile flows from your gallbladder or liver to your small intestine. Jaundice and bile duct infection (cholangitis) can result.
  • Blockage of the pancreatic duct. The pancreatic duct is a tube that runs from the pancreas to the common bile duct. Pancreatic juices, which aid in digestion, flow through the pancreatic duct. A gallstone can cause a blockage in the pancreatic duct, which can lead to inflammation of the pancreas (pancreatitis). Pancreatitis causes intense, constant abdominal pain and usually requires hospitalization. 
  • Gallbladder cancer. People with a history of gallstones have an increased risk of gallbladder cancer. But gallbladder cancer is very rare, so even though the risk of cancer is elevated, the likelihood of gallbladder cancer is still very small.
References
  1. Gallstones. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/gallstones/index.htm. Accessed May 28, 2009.
  2. Understanding gallstones. American Gastroenterological Association. http://www.gastro.org/wmspage.cfm?parm1=5680. Accessed May 28, 2009.
  3. Choi Y, et al. Biliary tract disorders, gallbladder disorders and gallstone pancreatitis. American College of Gastroenterology. http://www.acg.gi.org/patients/gihealth/biliary.asp?mode=print&. Accessed May 28, 2009.
  4. Browning JD, et al. Gallstone diseases. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/140200591-2/0/1389/0.html. Accessed May 28, 2009.
  5. What are the risk factors for gallbladder cancer? American Cancer Society. Accessed June 8, 2009.
  6. Rakel D. Cholelithiasis. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/142209696-2/0/1494/0.html. Accessed June 8, 2009.
  7. Venneman NG, et al. Gallstone disease: Primary and secondary prevention. Best Practice & Research Clinical Gastroenterology. 2006;20:1063.

DS00165

July 25, 2009

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