Gene therapy

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

Definition

By Mayo Clinic staff

Gene therapy involves altering the genes inside your body's cells to stop disease. Genes contain your DNA — the code that controls much of your body's form and function. Your cells use the information from your genes to manufacture proteins that do the work in your body, from making you grow taller to regulating your body systems. Throughout your life, your genes turn on and off as needed to control cell activity.

Genes that don't work properly can cause disease. Gene therapy replaces a faulty gene or adds a new gene in an attempt to cure disease or make changes in your body so it's better able to combat disease. Gene therapy holds promise for treating a wide range of diseases, including cancer, cystic fibrosis, heart disease, diabetes, hemophilia and AIDS.

Researchers are still learning about how gene therapy works and the best way to administer gene therapy. Currently, in the United States, gene therapy is available only as part of a clinical trial.

MY00105

Sept. 19, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger