Gilbert syndrome

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Definition

By Mayo Clinic staff

Gilbert (zheel-BAYR) syndrome is a common, mild liver disorder in which the liver doesn't properly process a substance called bilirubin. Bilirubin is produced by the breakdown of red blood cells. Also known as constitutional hepatic dysfunction, unconjugated benign bilirubinemia and familial nonhemolytic jaundice, Gilbert syndrome typically doesn't require treatment or pose serious complications.

In fact, Gilbert syndrome is usually not considered a disease because of its benign nature. You most often find out you have the disorder by accident, when you have a blood test that shows elevated bilirubin levels.

Gilbert syndrome affects 3 percent to 7 percent of the U.S. population. Worldwide estimations vary, and no good measure exists. More males than females have the condition.

DS00743

April 18, 2008

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