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By Mayo Clinic staffGilbert syndrome is an inherited genetic disorder. Getting the disorder isn't related to lifestyle habits or environment.
The only way to theoretically prevent the condition is to keep parents from passing the abnormal gene that causes it on to their children. But more than half the people in the general population carry one copy of this abnormal gene, making it very common. If two people with this abnormal gene have a child, they may pass along the genetic defect that causes Gilbert syndrome — but not always. Not everyone who has two copies of this abnormal gene gets Gilbert syndrome. This means you may have the condition without a family history of it. In contrast, everyone with Gilbert syndrome does have two copies of this abnormal gene.