Gilbert syndrome

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Symptoms

By Mayo Clinic staff

Usually no symptoms, sometimes jaundice
As an inherited condition, Gilbert syndrome is present from birth. Although it rarely causes symptoms, it may raise bilirubin enough to produce mild jaundice.

While the bilirubin does not reach a dangerous level, the appearance of jaundice may be unsettling. Typically, excess bilirubin turns the whites of your eyes yellow before affecting the color of your skin. If the bilirubin level keeps rising, your skin may develop a yellowish tinge.

Possible symptoms
You may experience episodes of:

  • Fatigue
  • Weakness
  • Abdominal pain

However, it's not known if Gilbert syndrome actually causes such symptoms, or if they're related to stress or other conditions.

Factors that may increase symptoms
A number of factors may increase bilirubin if you have Gilbert syndrome. These may include:

  • Illness, including infections, such as a cold or the flu
  • Menstruation
  • Fasting or skipping meals
  • Dehydration
  • Overexertion

DS00743

April 18, 2008

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