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Definition

By Mayo Clinic staff

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Illustration showing enlarged thyroid
Enlarged thyroid

Your thyroid is a butterfly-shaped gland located at the base of your neck just below your Adam's apple. Sometimes the thyroid gland grows larger than normal — a condition known as goiter. Although goiters are usually painless, a large goiter can cause a cough and make it difficult for you to swallow or breathe.

The most common cause of goiter worldwide is a lack of iodine in the diet. In the United States, where most people use iodized salt, goiter is more often due to the over- or underproduction of thyroid hormones or to nodules that develop in the gland itself.

Treatment depends on the size of the goiter, your symptoms and the underlying cause. Small goiters that aren't noticeable and don't cause problems usually don't need treatment.

References
  1. Goiter. American Thyroid Association. http://www.thyroid.org/patients/brochures/Goiter_brochure.pdf. Accessed Oct. 1, 2008.
  2. Simple nontoxic goiter. The Merck Manuals Online Medical Library: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec12/ch152/ch152i.html. Accessed Oct. 1, 2008.
  3. Jameson JL, et al. Disorders of the Thyroid Gland. In: Fauci AS, et al. Harrison's Online. 17th edition. The McGraw-Hill Companies Inc.; 2008. http://www.accessmedicine.com/content.aspx?aID=2877579&searchStr=goiter. Accessed Nov. 28, 2008.
  4. LaFranchi S. Goiter and thyroid cancer in children. http://www.uptodate.com/home/index.html. Accessed Oct. 1, 2008.
  5. LaFranchi S. Clinical manifestations and diagnosis of hyperthyroidism in children and adolescents. http://www.uptodate.com/home/index.html. Accessed Oct. 1, 2008.
  6. Endocrinology update: Imaging the thyroid nodule. MayoClinic.org. http://www.mayoclinic.org/mcitems/mc5800-mc5899/mc5810-1207.pdf. Accessed Oct. 1, 2008.
  7. Iodine. The Merck Manuals Online Medical Library: Home Edition for Patients and Caregivers. http://www.merck.com/mmhe/sec12/ch155/ch155f.html. Accessed Oct. 2, 2008.
  8. Bauer DC, et al. Thyroid Disease. In: McPhee SJ, et al. Pathophysiology of Disease: An Introduction to Clinical Medicine. 5th edition. The McGraw-Hill Companies Inc.; 2006. http://www.accessmedicine.com/content.aspx?aID=2091040&searchStr=goiter. Accessed Nov. 28, 2008.
  9. Nontoxic goiter: Diffuse and nodular. In: Kronenberg HM, et al. Williams Textbook of Endocrinology. 11th edition. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/das/book/body/112198375-3/778390960/1555/77.html. Accessed Nov. 28, 2008.

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Jan. 9, 2009

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