Green tea (Camellia sinensis)

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Safety

The U.S. Food and Drug Administration does not strictly regulate herbs and supplements. There is no guarantee of strength, purity or safety of products, and effects may vary. You should always read product labels. If you have a medical condition, or are taking other drugs, herbs, or supplements, you should speak with a qualified healthcare provider before starting a new therapy. Consult a healthcare provider immediately if you experience side effects.

Allergies

People with known allergy/hypersensitivity to caffeine or tannin should avoid green tea. Skin rash and hives have been reported with caffeine ingestion.

Side Effects and Warnings

Studies of the side effects of green tea specifically are limited. However, green tea is a source of caffeine, for which multiple reactions are reported.

Caffeine is a stimulant of the central nervous system, and may cause insomnia in adults, children, and infants (including nursing infants of mothers taking caffeine). Caffeine acts on the kidneys as a diuretic (increasing urine and urine sodium/potassium levels and potentially decreasing blood sodium/potassium levels) and may worsen incontinence. Caffeine-containing beverages may increase the production of stomach acid and may worsen ulcer symptoms. Tannin in tea can cause constipation. Certain doses of caffeine can increase heart rate and blood pressure, although people who consume caffeine regularly do not seem to experience these effects in the long-term.

An increase in blood sugar levels may occur. Caffeine-containing beverages such as green tea should be used cautiously in patients with diabetes. In contrast, lowering of blood sugar levels from drinking green tea has also been reported in preliminary research. Additional study is needed in this area.

People with severe liver disease should use caffeine cautiously, as levels of caffeine in the blood may build up and last longer. Skin rashes have been associated with caffeine ingestion. In laboratory and animal studies, caffeine has been found to affect blood clotting, although effects in humans are not known.

Caffeine toxicity is possible with high doses. Chronic use can result in tolerance, psychological dependence, and may be habit forming. Abrupt discontinuation may result in withdrawal symptoms.

Several population studies initially suggested a possible association between caffeine use and fibrocystic breast disease, although more recent research has not found this connection. Limited research reports a possible relationship between caffeine use and multiple sclerosis, although evidence is not definitive in this area. Animal study reports that tannin fractions from tea plants may increase the risk of cancer, although it is not clear that the tannin present in green tea has significant carcinogenic effects in humans.

Drinking tannin-containing beverages such as tea may contribute to iron deficiency, and in infants, tea has been associated with impaired iron metabolism and microcytic anemia.

In preliminary research, green tea has been associated with decreased levels of estrogens in the body. It is not clear if significant side effects such as hot flashes may occur.

In human study, topical use of ointment containing Polyphenon E® may result in local irritation.

Pregnancy and Breastfeeding

Large amounts of green tea should be used cautiously in pregnant women, as caffeine crosses the placenta and has been associated with spontaneous abortion, intrauterine growth retardation, and low birth weight.

Caffeine is readily transferred into breast milk. Caffeine ingestion by infants can lead to sleep disturbances/insomnia.

NS_patient-green_tea

Portions of this document last updated:

Sept. 1, 2009

THIS EVIDENCE-BASED MONOGRAPH WAS PREPARED BY
THE NATURAL STANDARD RESEARCH COLLABORATION
(www.naturalstandard.com)


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