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Definition
By Mayo Clinic staff
Guillain-Barre syndrome is an uncommon disorder in which your body's immune system attacks your nerves. Weakness and numbness in your extremities are usually the first symptoms. These sensations can quickly spread, eventually paralyzing your whole body.
The exact cause of Guillain-Barre syndrome is unknown, but it is often preceded by an infectious illness such as a respiratory infection or the stomach flu. Luckily, Guillain-Barre syndrome is relatively rare, affecting only 1 or 2 people per 100,000.
In its most severe form, Guillain-Barre syndrome is a medical emergency requiring hospitalization. There's no known cure for Guillain-Barre syndrome, but several treatments can ease symptoms and reduce the duration of the illness. And most people do recover completely.
- Benatar M., et al. Guillain-Barre syndrome. In: Ferri FF. Ferri's Clinical Advisor 2009. St. Louis, Mo.: Mosby; 2008. http://www.mdconsult.com/das/book/body/130350733-11/0/1701/245.html. Accessed April 9, 2009.
- Guillain-Barre syndrome. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/gbs/detail_gbs.htm?css=print. Accessed April 7, 2009.
- Cruse RP. Overview of Guillain-Barre syndrome in children. http://www.uptodate.com/home/index.html. Accessed April 7, 2009.
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- Shields RW, et al. Demyelinating disorders of the peripheral nervous system. In: Goetz GG. Textbook of Clinical Neurology. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/130350733-10/0/1488/410.html. Accessed April 7, 2009.
- Vriesendorp FJ. Treatment and prognosis of Guillain-Barre syndrome in adults. http://www.uptodate.com/home/index.html. Accessed April 7, 2009.
- Guillain-Barre syndrome (GBS). The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec16/ch223/ch223c.html?qt=guillain-barre&alt=sh . Accessed May 5, 2009.
- Seasonal flu and Guillain-Barre syndrome (GBS). Centers for Disease Control and Prevention. http://www.cdc.gov/FLU/about/qa/gbs.htm. Accessed May 5, 2009.
