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Definition

By Mayo Clinic staff

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Illustration showing thyroid Thyroid

Hashimoto's disease is a disorder that affects your thyroid, a small gland located at the base of your neck, below your Adam's apple. The thyroid gland is part of your endocrine system, which produces hormones that coordinate many of your body's activities.

In Hashimoto's disease, also known as chronic lymphocytic thyroiditis, your immune system attacks your thyroid gland. The resulting inflammation often leads to an underactive thyroid gland (hypothyroidism). Hashimoto's disease is the most common cause of hypothyroidism in the United States.

Doctors test your thyroid function to help detect Hashimoto's disease. Treatment of Hashimoto's disease with thyroid hormone replacement usually is simple and effective.

Symptoms
References
  1. Hashimoto's Disease: What it is and how it's treated. American Academy of Family Physicians. http://familydoctor.org/online/famdocen/home/common/hormone/548.html. Accessed December 9, 2008.
  2. Hennessey J, et al, eds. Hashimoto's disease. The Hormone Foundation. http://www.hormone.org/Resources/Thyroid/loader.cfm?csModule=security/getfile&pageid=1113. Accessed December 9, 2008.
  3. Brent GA, et al. Hypothyroidism and thyroiditis. In: Kronenberg HM, et al, eds. Williams Textbook of Endocrinology. 11th ed. St. Louis, Mo.: W.B. Saunders; 2008:387.
  4. Davies, TF. Pathogenesis of Hashimoto's thyroiditis (chronic autoimmune thyroiditis). http://www.uptodate.com/home/index.html. Accessed December 9, 2008.
  5. Frequently asked questions: Hashimoto's thyroiditis. US Department of Health & Human Services. http://www.4woman.gov/faq/hashimoto-thyroiditis.cfm. Accessed December 9, 2008.
  6. Hashimoto's thyroiditis. The Merck Manuals Online Medical Library: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec12/ch152/ch152d.html. Accessed December 9, 2008.
  7. Ross DS. Treatment of hypothyroidism. http://www.uptodate.com/home/index.html. Accessed December 9, 2008.

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Feb. 3, 2009

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