High blood pressure (hypertension)

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continued:

Central-acting agents

Uses for central-acting agents

Doctors prescribe central-acting agents to prevent, treat or improve symptoms in conditions, such as:

  • High blood pressure
  • Hot flashes
  • Alcohol or drug withdrawal
  • Attention-deficit/hyperactivity disorder (ADHD)
  • Tourette syndrome

Side effects and cautions

These medications can have strong side effects, so they aren't commonly used. Side effects include:

  • Extreme fatigue
  • Drowsiness or sedation
  • Dizziness
  • Impotence
  • Constipation
  • Dry mouth
  • Headache
  • Weight gain
  • Impaired thinking
  • Psychological problems, such as depression

Abruptly stopping use of some central-acting agents can cause a sudden, dangerous increase in blood pressure. Don't stop taking these medications, especially if you are taking a beta blocker, without talking to your doctor.

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References
  1. Clonidine: Martindale — The Complete Drug Reference. Micromedex Healthcare Series. http://www.micromedex.com/. Accessed Nov. 18, 2008.
  2. Sheps SG, ed. Mayo Clinic 5 Steps to Controlling High Blood Pressure. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2008:195.
  3. Initial antihypertensive therapy: Drugdex Consults. Micromedex Healthcare Series. http://www.micromedex.com/. Accessed Nov. 12, 2008.
  4. Blood pressure-lowering drugs. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=159. Accessed Nov. 12, 2008.

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Dec. 18, 2008

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