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Definition
By Mayo Clinic staffHirschsprung's disease is a condition that affects the large intestine (colon) and causes problems with passing stool. It's present when a baby is born (congenital) and results from missing nerve cells in the muscles of a portion of the baby's colon.
Children with Hirschsprung's disease can be constipated or have problems absorbing nutrients from food. In severe cases of Hirschsprung's disease, a newborn child experiences an obstructed colon and is unable to have a bowel movement. In mild cases, doctors may not detect Hirschsprung's disease until later in a child's life.
Surgical removal of the diseased portion of the child's colon is the only treatment for Hirschsprung's disease. After surgery, nine out of 10 children pass stool normally.
- What I need to know about Hirschsprung's disease. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/hirschsprungs_ez/. Accessed Sept. 12, 2008.
- Hirschsprung's disease. American Academy of Pediatrics. http://familydoctor.org/online/famdocen/home/children/parents/special/birth/906.htm. Accessed Sept. 12, 2008.
- Wesson, DE. Congenital ananglionic megacolon (Hirschsprung disease). http://www.uptodate.com/home/index.html. Accessed Sept. 12, 2008.
- Hirschsprung's disease. American Pediatric Surgical Association. http://www.eapsa.org/parents/resources/hirschsprungs.cfm. Accessed Sept. 12, 2008.
- Hirschsprung's disease. Family Practice Notebook. http://www.fpnotebook.com/GI/Neuro/HrschsprngsDs.htm. Accessed Sept. 12, 2008.
- Endom E. Emergency complications of Hirschsprung disease. http://www.uptodate.com/home/index.html. Accessed Sept. 12, 2008.
- Picco M [expert opinion]. Mayo Clinic, Rochester, Minn. Sept. 17, 2008.
