Intrauterine insemination (IUI)

Mayo Clinic Health Manager

Get free personalized health guidance for you and your family.

Get Started

Free

E-Newsletter

Subscribe to receive the latest updates on health topics. About our newsletters

  • Housecall
  • Alzheimer's caregiving
  • Living with cancer

How you prepare

By Mayo Clinic staff

Intrauterine insemination involves several steps before the actual procedure. First, your partner will provide a semen sample at the doctor's office. Similarly, a donor sperm vial can be thawed and prepared. Because nonsperm elements in semen can cause reactions in the woman's body that interfere with fertilization, the sample will be "washed" in a way that separates the highly active, normal sperm from lower quality sperm and other elements. The likelihood of achieving pregnancy increases by using a small, highly concentrated sample of healthy sperm.

Then, because the timing of IUI is so crucial, your doctor may monitor you for signs of impending ovulation using a transvaginal ultrasound, which is a machine that lets your doctor visualize your ovaries and egg growth. Alternatively, you may be asked to monitor yourself using an at-home urine ovulation predictor kit.

Just before ovulation, your body produces a surge or release of luteinizing hormone (LH). If you're coordinating IUI with your normal cycle, you'll go in for insemination the day after the LH surge. If you're using ovulation-inducing medications, you may be given an injection of human chorionic gonadotropin (hCG) to make you ovulate, and then go in for the insemination the next day.

MY00104

Aug. 29, 2008

© 1998-2009 Mayo Foundation for Medical Education and Research (MFMER). All rights reserved. A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.com," "EmbodyHealth," "Reliable tools for healthier lives," "Enhance your life," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.

Print Share Reprints

Text Size: smaller largerlarger