Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedCauses
By Mayo Clinic staffThe underlying cause of Legg-Calve-Perthes disease — also known as ischemic (avascular) necrosis of the hip — isn't clear. But what happens is this: There's a temporary loss of blood supply to the ball portion of the hip joint (femoral head). Without an adequate blood supply, the femoral head deteriorates. As dying bone cells are replaced with new cells, the bone becomes unstable, and may break easily and heal poorly.