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By Mayo Clinic staffSigns and symptoms of acute liver failure may include:
- A yellowing of your skin and eyeballs (jaundice)
- Tenderness in the upper right area of your abdomen
- Nausea
- Vomiting
- A general sense of not feeling well
- Difficulty concentrating
- Disorientation or confusion
- Sleepiness
- Muscle tremors
When to see a doctor
Acute liver failure can develop quickly in an otherwise healthy person, and it is life-threatening. If you or someone you know suddenly develops a yellowing of the eyes or skin, tenderness in the upper abdomen or any unusual changes in mental state, personality or behavior, seek medical attention right away.
- Polson J, et al. AASLD position paper: The management of acute liver failure. Hepatology. 2005;41:1179.
- Fontana RJ. Acute liver failure. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/135942637-3/0/1389/0.html. Accessed May 7, 2009.
- Fontana RJ. Acute liver failure including acetaminophen overdose. The Medical Clinics of North America. 2008;92:761.
- Liver health tips. American Association for the Study of Liver Diseases. http://www.aasld.org/yourliver/Pages/LiverHealthTips.aspx. Accessed May 7, 2009.