Monoclonal gammopathy of undetermined significance

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Coping and support

By Mayo Clinic staff

Although you can't control whether monoclonal gammopathy of undetermined significance will lead to something more serious, you can control many aspects of your health. The following suggestions may help:

  • Learn what you can about monoclonal gammopathy of undetermined significance. Write down any questions that come up and ask your doctor about them during your next appointment. Ask your health care team about resources for more information. The better you understand what's going on in your body, the more you'll be able to take an active role in your health care.
  • Control what you can about your health. Living a healthy lifestyle won't reduce your risk of complications in the future, but it can make you feel better and reduce your risk of other diseases and conditions. Eat a variety of fruits and vegetables. Get regular exercise. Get enough sleep so that you wake feeling rested. Reduce the amount of stress in your life.
  • Stick to your checkup schedule. Follow your doctor's checkup schedule and get the tests to check for more-serious diseases. Though you might be nervous about receiving your test results, diagnosing a serious condition, such as cancer, in the early stages may improve your chance for a cure.
References
  1. Monoclonal gammopathy. MayoClinic.org. http://www.mayoclinic.org/monoclonal-gammopathy. Accessed Sept. 5, 2008.
  2. Monoclonal gammopathy: Treatment. MayoClinic.org. http://www.mayoclinic.org/monoclonal-gammopathy/treatment.html. Accessed Sept. 5, 2008.
  3. Monoclonal gammopathies of undetermined significance (MGUS). The Merck Manuals Online Medical Library. http://www.merck.com/mmhe/sec14/ch175/ch175b.html. Accessed Sept. 5, 2008.
  4. Kyle RA, et al. Monoclonal gammopathy of undetermined significance. British Journal of Haemotology. 2006;134(6):573-589.
  5. Gertz M. What is monoclonal gammopathy of undetermined significance? International Myeloma Foundation. http://myeloma.org/main.jsp?type=article&id=879. Accessed Sept. 5, 2008.
  6. Rajkumar SV, et al. Recognition of monoclonal proteins. http://www.uptodate.com/home/index.html. Accessed Sept. 5, 2008.
  7. New Mayo study shows higher prevalence of MGUS, a pre-cancerous blood disorder, than previously suspected. MayoClinic.org. http://www.mayoclinic.org/news2006-rst/3302.html. Accessed Sept. 5, 2008.
  8. Landgren O, et al. Risk of monoclonal gammopathy of undetermined significance (MGUS) and subsequent multiple myeloma among African American and white veterans in the United States. Blood. 2006;107(3):904-906.

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Dec. 6, 2008

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