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By Mayo Clinic staffWhat causes morning sickness isn't entirely clear, but the hormonal changes of pregnancy are thought to play a role. Rarely, severe or persistent nausea or vomiting may be caused by a medical condition unrelated to pregnancy — such as thyroid or liver disease.
- Funai EF. Hyperemesis gravidarum and morning sickness. http://www.uptodate.com/home/index.html. Accessed June 29, 2009.
- Hill CC, et al. Physiologic changes in pregnancy. Surgical Clinics of North America. 2008;88:391.
- Morning sickness. The American College of Obstetricians and Gynecologists. http://www.acog.org/publications/patient_education/bp126.cfm. Accessed June 30, 2009.
- You and your baby: Prenatal care, labor and delivery, and postpartum care. The American College of Obstetricians and Gynecologists. http://www.acog.org/publications/patient_education/ab005.cfm. Accessed June 30, 2009.
- Holst L, et al. The use and the user of herbal remedies during pregnancy. The Journal of Alternative and Complementary Medicine. 2009;15:1.
- Goodwin TM. Hyperemesis gravidarum. Obstetrics and Gynecology Clinics of North America. 2008;35:401.
- Ginger. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed July 1, 2009.
- Acupressure. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed July 1, 2009.
- Mason MC. Pain relief to a point. Nursing Standard. 2008;22:22.
- Simon EP, et al. Medical hypnosis for hyperemesis gravidarum. Birth. 1999;26:248.
- Czeizel AE, et al. The effect of periconceptional multivitamin-mineral supplementation on vertigo, nausea and vomiting in the first trimester of pregnancy. Archives of gynecology and obstetrics. 1992;251:181.
- Emelianova S, et al. Prevalence and severity of nausea and vomiting of pregnancy and effect of vitamin supplementation. Clinical and Investigative Medicine. 1999;22:106.
- Gill SK, et al. The effectiveness of discontinuing iron-containing prenatal multivitamins on reducing the severity of nausea and vomiting of pregnancy. Journal of Obstetrics and Gynaecology. 2009;29:13.
- Harms RW (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 9, 2008.