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Definition
By Mayo Clinic staff
Multiple myeloma is a cancer of your plasma cells, a type of white blood cell present in your bone marrow. Plasma cells normally make proteins called antibodies to help you fight infections.
In multiple myeloma, a group of abnormal plasma cells (myeloma cells) multiplies, raising the number of plasma cells to a higher than normal level. Since these cells normally make proteins, the level of abnormal proteins in your blood also may go up. Health problems caused by multiple myeloma can affect your bones, immune system, kidneys and red blood cell count.
If you have multiple myeloma but don't have symptoms, your doctors may just monitor your condition. If you're experiencing symptoms, a number of treatments are available to help control multiple myeloma.
- Rajkumar SV, et al. Multiple myeloma and related disorders. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008. http://www.mdconsult.com/das/book/body/145977116-5/856340478/1709/160.html#4-u1.0-B978-0-443-06694-8..50114-7_4940. Accessed June 12, 2009.
- Konrad CN, et al. Multiple myeloma: Diagnosis and treatment. American Family Physician. 2008;78:853.
- Rajkumar SV. Initial chemotherapy for patients with high risk multiple myeloma. http://www.uptodate.com/home/index.html. Accessed June 12, 2009.
- Rajkumar SV. Initial chemotherapy for symptomatic multiple myeloma in patients who are not candidates for transplantation. http://www.uptodate.com/home/index.html. Accessed June 12, 2009.
- Treatment of the complications of multiple myeloma. http://www.uptodate.com/home/index.html. Accessed June 12, 2009.
- Detailed guide: Multiple myeloma. Chemotherapy and other drugs. American Cancer Society. Accessed June 12, 2009.
- Multiple myeloma: Moving on after treatment. American Cancer Society. Accessed June 12, 2009.
- Richardson PG, et al. Management strategies for relapsed multiple myeloma: Therapy in practice. American Journal of Cancer. 2006;5:393.
- Detailed guide: Multiple myeloma. What are the risk factors for multiple myeloma? American Cancer Society. Accessed June 12, 2009.
- Multiple myeloma: What are some questions I can ask my doctor? American Cancer Society. Accessed June 12, 2009.
- Integrative medicine & complementary and alternative therapies as part of blood cancer care. The Leukemia & Lymphoma Society. http://www.leukemia-lymphoma.org/attachments/National/br_1150734030.pdf. Accessed June 12, 2009.
- Complementary and alternative methods for cancer management. American Cancer Society. http://www.cancer.org/docroot/ETO/content/ETO_5_1_Introduction.asp. Accessed June 12, 2009.
- Rajkumar SV (expert opinion). Mayo Clinic, Rochester, Minn. July 8, 2008.
