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By Mayo Clinic staffDiagnosis is typically based on your skin's appearance and a history of itching and scratching. Your doctor may recommend one of the following tests to rule out other causes or to confirm the diagnosis.
- Patch testing. A patch test (contact delayed hypersensitivity allergy test) can rule out other causes of itchy skin, such as allergic contact dermatitis. During a patch test, small quantities of potential allergens are applied to small patches, which are then placed on your skin. The patches remain on your skin for two days, and then your doctor checks for a reaction. If you're allergic to a particular substance being tested, you develop a raised bump or a reaction limited to the skin just beneath the patch.
- Punch biopsy. During a punch biopsy test, the doctor uses a circular tool to remove a small section of your skin's deeper layers. A punch biopsy extends about 1/4 inch (6 millimeters) deep. You'll likely receive stitches to close the wound.