Mayo Clinic Health Manager
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By Mayo Clinic staffIn most cases, night leg cramps have no identifiable cause. However, night leg cramps may sometimes be associated with:
- Addison's disease
- Alcoholism
- Choosing blood pressure medications
- Cirrhosis
- Dehydration
- Type 2 diabetes
- Diarrhea
- Diuretics
- Electrolyte imbalance
- Flatfeet
- Gastric bypass surgery
- Hypothyroidism (underactive thyroid)
- Kidney failure, chronic
- Muscle fatigue
- Oral contraceptives
- Parkinson's disease
- Second trimester pregnancy: What to expect
- Peripheral artery disease (PAD)
Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.
- Kanaan N, et al. Nocturnal leg cramps: Clinically mysterious and painful - but manageable. Geriatrics. 2001;56:34.
- Walters AS. Clinical identification of the simple sleep-related movement disorders. Chest. 2007;131:1260.
- Sheon RP. Nocturnal leg cramps, night starts and nocturnal myoclonus. http://www.uptodate.com/home/index.html. Accessed Dec. 8, 2008.
- Dehydration and fluid maintenance. Columbia, Md.: American Medical Directors Association. http://www.guideline.gov/summary/summary.aspx?ss=15&doc_id=3305&nbr=2531. Accessed Dec. 9, 2008.