Nonalcoholic fatty liver disease

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Tests and diagnosis

By Mayo Clinic staff

Tests and procedures used to diagnose nonalcoholic fatty liver disease include:

  • Blood tests. Liver function tests, including tests of liver enzymes, may help your doctor make a diagnosis.
  • Imaging procedures. Imaging procedures used to diagnose fatty liver disease include ultrasound, computerized tomography (CT) scan and magnetic resonance imaging (MRI).
  • Liver tissue testing. If it's suspected that you have a more serious form of nonalcoholic fatty liver disease, your doctor may recommend a procedure to remove a sample of tissue from your liver (liver biopsy). The tissue sample is examined in a laboratory to look for signs of inflammation and scarring. Liver biopsy is typically done using a long needle inserted through your skin and into your liver to remove liver cells (needle biopsy).
References
  1. Feldstein AE, et al. Fatty liver disease. The American College of Gastroenterology. http://www.acg.gi.org/patients/gihealth/fld.asp. Accessed Jan. 6, 2009.
  2. Fatty liver. American Liver Foundation. http://www.liverfoundation.org/education/info/fattyliver/. Accessed Jan. 6, 2009.
  3. Reid AE. Nonalcoholic fatty liver disease. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2006. http://www.mdconsult.com/das/book/body/115719609-2/0/1389/588.html?tocnode=51641781&fromURL=588.html#4-u1.0-B1-4160-0245-6..50087-1_3674. Accessed Jan. 6, 2009.
  4. Nonalcoholic steatohepatitis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/nash/index.htm. Accessed Jan. 6, 2009.
  5. Preiss D, et al. Non-alcoholic fatty liver disease: An overview of prevalence, diagnosis, pathogenesis and treatment considerations. Clinical Science. 2008;115:141.
  6. Torres DM, et al. Diagnosis and therapy of nonalcoholic steatohepatitis. Gastroenterology. 2008;134:1682.
  7. Sheth SG, et al. Nonalcoholic steatohepatitis. http://www.uptodate.com. Accessed Jan. 6, 2009.
  8. Moschen AR, et al. Nutrition in the pathophysiology and treatment of nonalcoholic fatty liver disease. Current Opinion in Clinical Nutrition and Metabolic Care. 2008;11:620.

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Feb. 19, 2009

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