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Causes
By Mayo Clinic staffDoctors don't know what causes Paget's disease of the breast. But one widely accepted theory is that Paget's disease of the breast results from an underlying ductal or invasive breast cancer. Cancer cells from the original tumor travel through milk ducts to the nipple and its surrounding skin (areola).
Another theory suggests that normal cells on the surface of your nipple spontaneously transform into cancer cells. In rare cases of Paget's disease of the breast, no underlying breast cancer can be found.
