Paranoid schizophrenia

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Risk factors

By Mayo Clinic staff

Although the precise cause of paranoid schizophrenia isn't known, researchers have identified certain factors that seem to increase the risk of developing or triggering paranoid schizophrenia, including:

  • Having a family history of schizophrenia
  • Exposure to viruses while in the womb
  • Malnutrition while in the womb
  • Stressful life circumstances
  • Trauma or abuse during childhood
  • Older paternal age
  • Taking psychoactive drugs during adolescence

According to the National Institute of Mental Health, schizophrenia affects about 1 percent of the general population, and paranoid schizophrenia affects an even smaller percentage. Schizophrenia typically becomes apparent between the teenage years and the mid-30s, but paranoid schizophrenia may start later in life.

References
  1. Schizophrenia and other psychotic disorders: Paranoid type. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed Oct. 30, 2008.
  2. Minzenberg MJ, et al. Schizophrenia. In: Hales RE, et al, eds. The American Psychiatric Publishing Textbook of Psychiatry. 5th ed. Arlington, Va.: American Psychiatric Publishing Inc.; 2008. www.psychiatryonline.com. Accessed Oct. 7, 2008.
  3. Schizophrenia. National Institute of Mental Health. http://www.nimh.nih.gov/health/publications/schizophrenia/complete-publication.shtml. Accessed Oct. 27, 2008.
  4. Jibson MD, et al. Schizophrenia and related disorders. http://www.uptodate.com/home/index.html. Accessed Oct. 1, 2008.
  5. Schizophrenia and other psychotic disorders: Schizophrenia. In: Diagnostic and Statistical Manual of Mental Disorders DSM-IV-TR. 4th ed. Arlington, Va.: American Psychiatric Association; 2000. http://www.psychiatryonline.com. Accessed Oct. 30, 2008.
  6. Dyer JG, et al. Update on early intervention in schizophrenia. Journal of Psychosocial Nursing. 2008;46:19.
  7. Turkington D, et al. Cognitive behavior therapy for schizophrenia. American Journal of Psychiatry. 2006;163:365.
  8. Treating schizophrenia. A quick reference guide. Arlington, Va.: American Psychiatric Association. http://www.psychiatryonline.com/. Accessed Dec. 9, 2008.
  9. Schultz SH, et al. Schizophrenia: A review. American Family Physician. 2007;75:1821.
  10. Treatment of patients with schizophrenia, 2nd ed. Arlington, Va.: American Psychiatric Association. http://www.psychiatryonline.com/. Accessed Dec. 9, 2008.

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Dec. 16, 2008

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