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By Mayo Clinic staffPossible complications of pemphigus are infection of your skin and spread of infection through your bloodstream (sepsis). Systemic infection can be fatal.
Complications of paraneoplastic pemphigus include respiratory problems. The mortality rate for this type of pemphigus is estimated to be 90 percent, independent of the underlying cancer.
Other complications are the possible side effects of the medications used to treat pemphigus, particularly corticosteroids.