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Definition
By Mayo Clinic staffPerimenopause marks the interval in which your body begins its transition into menopause. Perimenopause encompasses the years leading up to menopause — anywhere from two to eight years — plus the first year after your final period. It's a natural part of aging that signals the ending of your reproductive years.
Your estrogen level rises and falls unevenly during perimenopause. Your menstrual cycles may lengthen or shorten, and you begin having menstrual cycles in which you don't ovulate. It's only during cycles when you do ovulate that you can become pregnant.
When perimenopause starts and how long it lasts varies. You'll probably notice signs of impending menopause, such as menstrual irregularity, sometime in your 40s. But some women notice changes as early as their mid-30s.
