Peritoneal dialysis

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Results

By Mayo Clinic staff

Many factors affect how well peritoneal dialysis works in removing wastes and extra fluid from your blood. These factors include:

  • Your size
  • How quickly your peritoneum filters waste (peritoneal transport rate)
  • How much dialysis solution you use (fill volume)
  • The number of daily exchanges
  • Dwell times
  • The concentration of sugar (dextrose) in the dialysis solution

Your health care team will perform several tests to check if your dialysis is removing enough waste products. These tests are especially important during the first weeks of dialysis to determine whether you're receiving an adequate amount, or dose.

  • Peritoneal equilibration test (PET). This test measures how much sugar has been absorbed from a bag of used dialysis solution and how much of two waste products — urea and creatinine — have entered into the solution during a four-hour exchange.
  • Clearance test. Samples of used dialysis solution and a blood sample are collected to compare the amount of urea in the used solution with the amount in the blood. If you still produce urine, your doctor may take a urine sample at the same time to measure its urea concentration.

If the test results show that your dialysis schedule is not removing enough wastes, your doctor may change your prescription. This might involve changing the number of exchanges, increasing the amount of solution you use for each exchange or using a dialysis solution with a higher concentration of dextrose, a type of sugar.

You can improve your dialysis results and your overall health by eating the right foods, including foods low in sodium and phosphorus and high in protein. Your dietitian will help you develop an individualized meal plan based on your weight, your personal preferences, your remaining kidney function and other medical conditions, such as diabetes or high blood pressure.

Taking your medications as prescribed also is important for achieving the best possible results. While you're receiving peritoneal dialysis, you'll likely need various medications to control your blood pressure, stimulate production of red blood cells, control the levels of certain nutrients in your blood and prevent the buildup of phosphorus in your blood.

References
  1. Dialysis in the treatment of renal failure. In: Fauci AS, et al, eds. Harrison's Principles of Internal Medicine. 17th ed. United States of America: The McGraw-Hill Companies Inc.; 2008. http://www.accessmedicine.com/popup.aspx?aID=2881062&print=yes. Accessed Aug. 24, 2008.
  2. Peritoneal dialysis: What you need to know. National Kidney Foundation. https://www.kidney.org/atoz/atozItem.cfm?id=197. Accessed Sep. 10, 2008.
  3. Treatment methods for kidney failure: Peritoneal dialysis. National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC). http://kidney.niddk.nih.gov/Kudiseases/pubs/peritoneal/. Accessed Sep. 10, 2008.
  4. Berns JS. Patient information: Renal replacement therapy. http://www.uptodate.com/home/index.html. Accessed Aug. 26, 2008.
  5. Mailloux LU. Dialysis modality and patient outcome. http://www.uptodate.com/home/index.html. Accessed Aug. 26, 2008.
  6. Peritoneal dialysis dose and adequacy. National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC). http://kidney.niddk.nih.gov/Kudiseases/pubs/peritonealdose/. Accessed Sep. 10, 2008.
  7. Berns JS. Patient information: Chronic kidney disease. http://www.uptodate.com/home/index.html.
  8. Gajjar AH. Peritoneal dialysis catheters: Laparoscopic versus traditional placement techniques and outcomes. The American Journal of Surgery. 2007;194:872.

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Dec. 12, 2008

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